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Muscle cramps are common during pregnancy and calcium deficiency can also cause pregnant women to have spasms. Various unhealthy lifestyle practices can cause hand cramping including excessive alcohol consumption poor sleep poor diet and taking medications like diuretics. If You Regularly Suffer From Hand Cramps Take Our Advice Some of the main causes of muscle cramps include electrolyte imbalances dehydration and overuse of the muscle. Why does my hand keep cramping . Bed soap prevents her night-time leg cramps. Cramping can be caused by dehydration electrolyte abnormalities overuse or deconditioning of muscles says Kelly Weselman MD a rheumatologist with WellStar Medical Group in Smyrna Georgia. The kidney disease can cause the cramp because of the imbalanced fluid and nerve damage. Report Delete Reply. Spasms or cramps are involuntary contractions in the hands or feet. The median nerve provides sensation to the aforementioned fingers which is why patients generally have